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EN
Guide RNAs [TCCCGATGCCACTGTCGCTC and GAGACTATCCCGAGCGACAG] were originally designed to introduce a point mutation in exon 4. DNA sequencing of the targeted region identified genome edited pups harboring a Setbp1 98-nt frameshift deletion (indel mutation) that starts at Pro-857 and introduces a TGA stop codon immediately afterwards [GCGAGGAGACTATCCC//del98//TTGACAACCCAGAGGCC]. (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
