The construct incorporates an FRT-lacZ-loxP followed by a neomycin resistance cassette, SV40 polyA, a second FRT site and a second loxP site in intron 3. A third loxP site is inserted downstream in intron 5 (position 78855613). Flp-mediated recombination removed the FRT-flanked lacZ and neo cassette leaving exon 4 floxed. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion
--
1
13
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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