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EN
Plasmids encoding guide RNA (ATG GCT GGG GCT CGG CGC GGC TGG CGG CTG TCG) were designed to introduce guanine to thymine point mutation in exon 1. The resulting exon 1 harbors an alanine to serine mutation at amino acid position 11 (A11S). There are no known off-target sites present. The A11S mutation in orthologous to the human A9S mutation found in Christianson syndrome patients. (J:284697)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
