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The human 4 repeat tau containing the P301L mutation and myc and FLAG tags at the N- and C-terminals, respectively, is under the control of the Camk2 promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled. Mice show a 3-5-fold overexpression of the mutant tau relative to endogenous mouse tau. (J:167329)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
