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The allele was generated by constructing a targeting vector encoding the self-cleaving peptide T2A followed by the iCre gene and a frt-flanked neomycin resistance gene to be inserted immediately 3' of the last Ighg3 transmembrane exon. The neo cassette was removed by Flp-mediated recombination in the chimeric mice. (J:278686)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
