The transgenic construct is designed with a bidirectional tetracycline responsive promoter containing the Tet-responsive element (TRE or tetO7 seven copies of the 42-bp tet operator sequence [tetO]) directing expression of the mouse Twist1 gene on one side and the luciferase (luc) gene on the other side. (J:185196)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count