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Using bacterial recombineering technology, BAC RP24-68P2 containing the entire Krt19 was used to generate a transgene with a iCre-polyA cassette replacing the ATG codon and the following 632 bps of the coding sequence in the Krt19 gene. Twelve founder lines were generated. Line 2 and 5 heterozygous showed no health issue, and the line #2 was used for the studies. (J:279102)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
