A cDNA encoding IRES-cre recombinase fused with a mutant form of estrogen receptor hormone-binding domain C (ERT2) was inserted after the site encoding the translational stop codon of the Sox9 gene, using the CRISPR/Cas9 technology. (J:269510, J:278073)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count