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The targeting construct inserted into the locus a CAGGS promoter (CAG), a floxed PGK-puromycin STOP cassette (LSL), the mouse Dnd1 cDNA with N-terminal FLAG and myc tags, and an frt site. Upon cre-mediated excision of the STOP cassette, the minigene constitutively expresses the FLAG/myc tagged Dnd1 driven by the CAG promoter. (J:281756)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
