Three transgenes were co-injected expressing cas9 under the conrol of the ubiquitous CAG promoter, Rnu6 promoter driving expression of a guide RNA targeting Trp52 and agouti allele under the control of the Krt14 promoter. The E3B line was generated. (J:283235)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count