Three transgenes were co-injected expressing cas9 under the conrol of the ubiquitous CAG promoter, Rnu6 promoter driving expression of a guide RNA targeting Trp52 and agouti allele under the control of the Krt14 promoter. The E3B line was generated. (J:283235)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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