CRISPR/Cas9 genome editing is used to introduce a 5' HA tag, an EGFP reporter, an IRES, and a DTR with an SV40 polyadenylation sequence and 3' HA tag into exon 1, following the ATG codon. The insertion results in a 53 bp deletion in the remainder of exon 1. (J:253628)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count