A loxP site was introduced to intron 4 and an frt-PGK-Neo-frt-loxP selection cassette was placed in intron 5. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:280408)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count