The targeting vector is designed to insert Cre cassettes under the control of the Tlr2 promoter by BAC recombineering. After homologous recombination in ES cells, open reading frame of Tlr2 exon 3 was substituted with Cre. (J:281617)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count