CRISPR/Cas9 endonuclease-mediated genome editing was used to insert loxP sites flanking exon 1. Cre-mediated recombination removed exon 1. (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count