A patient-derived human ALK cDNA followed by an IRES-beta geo-polyA selection cassette was fused in-frame to mouse exon 21. The floxed Neomycin resistance gene was deleted by Cre-mediated recombination. (J:230720)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count