Plasmids encoding a guide RNA were designed to introduce a K198R point mutation (AAA to AGA) as well as several nucleotide changes encoding silent mutations (F197F [TTC to TTT], G199G [GGT to GGC], Q201Q [GAG to GAA] and L203L [CTT to CTA]). (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
Insertion, Nucleotide substitutions
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1
2
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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