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A loxP site was inserted upstream of exon 4. A floxed cassette with a splice acceptor, IRES, and GFP reporter gene were inserted downstream of exon 4. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette previously located within the reporter cassette. Immunohistochemistry confirms the reduction in transcript expression in ARC neurons. (J:281818, J:277600)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
