The L1L2_Del_BactPneo_FFL cassette was inserted at position 27396587 of Chromosome 19 upstream of exon 1 (Build 37). The cassette is composed of an FRT site followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a loxP site. A second loxP site is inserted downstream of exon 1 at position 27398917. Exon 1 is thus flanked by loxP sites. Exon 1 was deleted through subsequent cre-mediated recombination.

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion, Intragenic deletion
--
1
8
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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