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A Cre cDNA, a polyadenylation signal (pA) from the human granulocyte-colony stimulating factor gene, a phosphoglycerate kinase (PGK) promoter-driven neomycin resistance gene (neo)-pA cassette (PGK-neo-pA cassette) flanked by two frt sites were inserted into the translation initiation site (in exon 2) of the mouse Slc6a5 gene by homologous recombination in ES cells. The PGK-neo-pA cassette was removed by crossing mice with FLP66 transgenic mice. (J:279620)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
