Two constructs consisting of one with a mouse Pdgfrb promotor driving Flp recombinase and another carring a Frt-Stop-Frt-CreERT2 cassette under the control of the mouse Cspg4 promoter were co-injected into C57BL/6 blastocysts via pronuclear injection. Five founder pups were identyfied as carrying both transgenes. One unnamed founder line was established and verified. The pound symbol (#) is used when no line name is specified and/or lines are pooled. (J:281538)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count