An FRT-lacZ-loxP-hACTB promoter-neomycin-FRT-loxP cassette was introduced to intron 6 and a loxP site was placed in intron 7. Flp-mediated recombination removed the FRT-flanked lacZ/neo cassette leaving exon 7 floxed. (J:281518)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count