A loxP site and a frt-flanked neomycin resistance gene were inserted upstream of exon 4 and a second loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette leaving exon 4 floxed. (J:265659)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count