A transgene derived from a BAC clone bMQ313M14 containing the mouse Drd2 (dopamine receptor D2) promoter modified to no longer drive expression of dopamine 2 receptors and expresses codon-optimized Flp (flpo) recombinase. No other genes are reported to be expressed from the BAC. The transgenic vector was introduced to FVB embryos. A loxP-flanked neomycin selection cassette originally located just 3' of Flp has been excised. This is founder line 3B. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
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Insertion
--
--
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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