This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GATGAGGAGGTCAGGAGTAA and CATGACACAATCAATCAGCC, which resulted in a 396 bp deletion beginning at Chromosome 7 position 127,723,008 bp and ending after 127,723,403 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000492582 (exon 2) and 256 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 8 and early truncation 6 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count