The transgene has (from 5' to 3'), an insulator sequence, the Adamts18 intronic enhancer region from between exons 2 and 3 (Chr8:113,848,193-113,845,196, mouse assembly mm10), an Hsp68 minimal promoter sequence, the rtTA gene and a polyA sequence. (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count