CRISPR-Cas9 technology was used to introduce deletion causing a frameshift mutaion in the coding region. The mutant Plet1 gene expresses a truncated Plet1 protein containing 53AA from plet1 with deletion from 54 aa-end (237aa). (J:251136)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count