CRISPR-targeting of exon 2 of Zfp418 gene generated mutations. Genotyping revealed the mutations comprised mostly deletions (2-12 bp), but also some insertions (2-3 bp). All mutations are in the target sequence. The pound (#) symbol is used for the pool of all alleles for this gene found in the knock-out founders. (J:251673)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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