An IKMC targeting vector was used to insert an FRT site, lacZ gene, loxP site, neomycin resistance gene, FRT site and loxP site upstream of exon 4 and a loxP site downstream of exon 6 via homologous recombination. Cre mediated recombination removed the neo cassette and exons 4 - 6. (J:277128)
Basic Information
(129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count