A loxP site was inserted 5' to exon 4 and an frt-flanked hygromycin selection cassette followed by a second loxP site was inserted 3' to exon 5. The neomycin selection cassette was removed by Flp-mediated recombination in the germline. (J:278155)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count