The coding exon 3 of the gene is flanked by loxP sites at the 5' end and a second loxP insertion at downstream of the stop codon so that Cre-mediated recombination will produce a deletion of entire coding region and splicing site. An frt-flanked neomycin selection cassette was removed via Flp-mediated recombination in the germline. (J:278651)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top