A loxP site and an frt-flanked neomycin selection cassette were inserted upstream of exon 7 and a single loxP site was inserted downstream of exon 8. The neomycin selection cassette was removed via Flp-mediated recombination. (J:231078)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count