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EN
A DNA fragment that contained a loxP sequence and pgk-1 promoter-driven neomycin phosphotransferase gene (Neo cassette) flanked by two Flp recognition target (frt) sites was inserted into a site 107 bp upstream of exon 11. The pgk-1 polyadenylation (poly-A) signal sequence was inserted downstream of the Neo cassette. The other loxP site was introduced into a site 113 bp downstream of exon 11 to eliminate the putative transmembrane domain after Cre-mediated recombination. (J:279639)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
