Insertion of a loxP-NeotpA-loxP cassette into the 1st intron (between exons 1 and 2) of the gene resulted in a null allele; restoration of gene expression is observed upon recombination of the loxP sites. (J:269263)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count