Exons 3-5 were flanked by loxP sites and a FRT-flanked neomycin resistance gene and F3-flanked puromycin resistance gene were inserted into intron 2 and intron 5, respectively. Flp-mediated recombination removed the selection makers leaving exons 3-5 floxed. (J:279270)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count