A site-specific integrase-mediated approach inserted attP site, attL site, CAG promoter, kinase dead cas9 gene, SV40 polyadenylation sequence and attR site. The targeting construct also contained an mCherry reporter gene and puromycin resistance cassette. (J:278806)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count