This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGTCTGTTCCACCAAGGTGG and GGTAATACTGGGAAGAACCC, which resulted in a 205 bp deletion beginning at Chromosome 8 position 70,229,504 bp and ending after 70,229,708 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001310569 (exon 3) and 122 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 41 and early truncation 1 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count