Try10em1(IMPC)J
Basic Information
Phenotypes
References Literature
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCAACATAGAGAGACTGTAG and ATTTGAATTCTGTACCATTA, which resulted in a 418 bp deletion beginning at Chromosome 6 position 41,355,213 bp and ending after 41,355,630 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001070396 (exon 2) and 258 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 13 and early truncation 4 amino acids later. (J:188991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
5
--
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
hm1(F)(0)
hm1(M)(0)
behavior/neurological
cardiovascular system
hematopoietic system
homeostasis/metabolism
immune system
References Literature
This section is currently in development, please stay tuned for our data updates.
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Comparison
Al agent
Sources
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