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A targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a CreER fusion gene followed by a frt-flanked neo cassette upstream of the stop codon of the adenylate cyclase activating polypeptide 1 (Adcyap1) gene. CreER incorporates cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain. The neomycin cassette was excised with Flp recombinase. (J:323692)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
