This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CGTCGATGCTAGTTGAGCCT and GTATGCAGGAGACAGAGCAC, which resulted in a 467 bp deletion beginning at Chromosome 6 position 138,150,680 bp and ending after 138,151,146 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001207752 (exon 3) and 372 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 42 and early truncation 4 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count