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The transgene was created by modifying BAC by replacing exon 2 of mouse Amelx gene with an improved cre recombinase gene (icre). An FRT-flanked kanomycin resistance cassette was removed prior to injection. 4 independent BAC founder lines (854, 863, 872, and 876) were collected. Line 854 showed the X-gal staining in ameloblasts and very light staining activity in the bone tissue. (J:278625)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
