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This allele is derived from Fbln7tm1Hiya. Cre-mediated recombination resulted in the excision of the floxed sequence containing exon 2 and an FRT-flanked neo cassette. qPCR analysis revealed a severe loss of expression in the cortex and medulla of homozygous mutant kidneys. In situ hybridization confirmed the absence of expression in mutant kidney sections at the cortex level. (J:271278)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
