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EN
A conventional homologous recombination approach in mouse embryonic stem (ES) cells was used for the targeted insertion of the tetracycline-controlled transactivator (tTA) into intron 1 of the endogenous eukaryotic translation elongation factor 1 alpha 1 (Eef1a1) locus. The tTA is preceded by a splice acceptor site and a floxed transcriptional Stop sequence (i.e., promoterless neo with three polyA signals). (J:292860)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
