An FRT and loxP-flanked neomycin resistance cassette was inserted 500 bp downstream of Mir221. Another loxP site was inserted 3000 bp upstream Mir222. Flp-mediated recombination removed the selection cassette and left the two microRNA floxed. (J:278082)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count