The targeting construct is designed to contain a loxP site upstream of exon 3, an EYFP reporter fused to the 3' end of exon 4, a polyA, and an FRT flanked neomycin cassette followed by a second loxP site. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:278343)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count