A bicistronic sequence coding for EGFP and loxP-stop-loxP-HcRed was placed downstream of human VAV1 promoter sequence and upstream of Vav1 enhancer sequence. The entire construct was flanked by two 250 bp core elements from chicken beta globulin insulator. Multiple founders were used to establish a colony, but founder lines were not analyzed separately. Characterization of this line revealed no HcRed fluorescence after Cre-mediated recombination of loxP sites. (J:278594)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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