Left TAL effector (50,244,600-50,244,616 bp) and right TAL effector (50,244,569-50,244,585 bp) separated by the FokI cleavage zone is used to introduce a frameshift deletion in the first coding exon. The mutation results in a premature stop codon. Founder 3 is established. (J:232145)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count