Left TAL effector (50,191,867-50,191,883 bp) and right TAL effector (50,191,899-50,191,915 bp) separated by the FokI cleavage zone is used to introduce a 16 bp frameshift deletion in the first coding exon (exon 4). The mutation results in a premature stop codon. Founder 28 is established. (J:232145)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
Intragenic deletion
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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