Cre-mediated excision of the Nintm1c(EUCOMM)Hmgu allele resulted in the deletion of exon 2. Immunoblotting and immunostaining analysis confirmed absence of protein in embryonic fibroblasts and skin sections, respectively. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:277726)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count