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The RMCE with the targeting vector introduced into the 3' UTR an inverted lox71/lox66-flanked CAG promoter driving ubiquitous expression of human cDNA with the amino acid substitution lysine for aspartic acid at position 17 (E17K; Open Biosystems 100067520), an IRES sequence and firefly luciferase (Luc2). (J:233376)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
