Cas9 mRNA and single-guide RNA (sgRNA) targeting exon 1 of mouse Padi2 was microinjected into the cytoplasm of zygote-stage embryos to induce deletions. The line that carried a frameshift mutation was selected. (J:278064)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count