Cas9 mRNA and single-guide RNA (sgRNA) targeting exon 1 of mouse Padi2 was microinjected into the cytoplasm of zygote-stage embryos to induce deletions. The line that carried a frameshift mutation was selected. (J:278064)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6D2F1
Endonuclease-mediated
Intergenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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